Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1

Acta Neuropathol. 2019 Mar;137(3):521-525. doi: 10.1007/s00401-019-01960-x. Epub 2019 Jan 16.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / genetics*
  • Brain Neoplasms / pathology*
  • Child
  • DEAD-box RNA Helicases / genetics*
  • Female
  • Humans
  • Inclusion Bodies / pathology
  • Male
  • Mutation, Missense
  • Neurofibromatosis 1 / complications
  • Ribonuclease III / genetics*
  • Sarcoma / genetics*
  • Sarcoma / pathology*
  • Young Adult

Substances

  • DICER1 protein, human
  • Ribonuclease III
  • DEAD-box RNA Helicases