Taming autoimmunity: Translating antigen-specific approaches to induce immune tolerance

J Exp Med. 2019 Feb 4;216(2):247-250. doi: 10.1084/jem.20182287. Epub 2019 Jan 16.

Abstract

José M. Carballido, Executive Director at Novartis Institutes for BioMedical Research, and Pere Santamaria, Professor of Immunology at the University of Calgary and Founder of Parvus Therapeutics Inc., discuss the opportunities and challenges of translating antigen-specific approaches for autoimmunity with an emphasis on the need for scientific rigor in the preclinical stage.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens*
  • Autoimmunity*
  • Humans
  • Immune Tolerance*

Substances

  • Antigens

Grant support