Early and sensitive detection of PML-A216V mutation by droplet digital PCR in ATO-resistant acute promyelocytic leukemia

Leukemia. 2019 Jun;33(6):1527-1530. doi: 10.1038/s41375-018-0298-3. Epub 2019 Jan 16.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / pharmacology*
  • Arsenic Trioxide / pharmacology*
  • Drug Resistance, Neoplasm*
  • Female
  • Follow-Up Studies
  • Humans
  • Leukemia, Promyelocytic, Acute / diagnosis
  • Leukemia, Promyelocytic, Acute / drug therapy
  • Leukemia, Promyelocytic, Acute / genetics*
  • Male
  • Middle Aged
  • Mutation*
  • Polymerase Chain Reaction / methods*
  • Prognosis
  • Promyelocytic Leukemia Protein / genetics*

Substances

  • Antineoplastic Agents
  • Promyelocytic Leukemia Protein
  • PML protein, human
  • Arsenic Trioxide