Complete amino acid sequence of a beta-galactoside-binding lectin from human placenta

J Biochem. 1988 Jul;104(1):1-4. doi: 10.1093/oxfordjournals.jbchem.a122401.

Abstract

The complete amino acid sequence of a beta-galactoside-binding lectin from human placenta was determined at protein level. The lectin consists of 134 amino acids and its N-terminal alanine is blocked with acetate. The lectin shows about 50% similarity with chick 14K lectin, which was the first vertebrate beta-galactoside-binding lectin completely sequenced. Only 14 residues proved to be different from those of rat lung lectin, the sole mammalian lectin of which the complete sequence has been reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Cyanogen Bromide
  • Female
  • Galactosides / metabolism
  • Galectins
  • Hemagglutinins* / isolation & purification
  • Humans
  • Molecular Sequence Data
  • Peptide Fragments / analysis
  • Peptide Hydrolases
  • Placenta / metabolism*
  • Pregnancy

Substances

  • Galactosides
  • Galectins
  • Hemagglutinins
  • Peptide Fragments
  • Peptide Hydrolases
  • Cyanogen Bromide