Lyme myelopathy: Case report and literature review of a rare but treatable disorder

Mult Scler Relat Disord. 2019 Apr:29:1-6. doi: 10.1016/j.msard.2018.12.034. Epub 2019 Jan 3.

Abstract

The differential diagnosis for transverse myelitis is extensive, and the prognosis is highly variable depending on the etiology. We describe a rare case of a 56-year-old previously healthy male who presented with thoracic paresthesias and hyperesthesias involving the T6-11 dermatomes several weeks after a febrile illness. A thoracic MRI demonstrated a T7-10 transverse myelitis, and an exhaustive evaluation revealed neuroborreliosis. His symptoms improved significantly after an initial steroid course and 21 day course of ceftriaxone. We review neuroborreliosis and summarize the features of 23 previously reported cases of Lyme myelopathy. Although Lyme myelopathy is rare, including Lyme in the differential diagnosis of an acute transverse myelitis work up is important in endemic regions, as it is a potentially reversible disorder with a generally good prognosis when appropriately treated with antibiotics.

Keywords: Lyme; Myelopathy; Neuroborreliosis; Transverse myelitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Humans
  • Lyme Neuroborreliosis / complications
  • Lyme Neuroborreliosis / diagnosis*
  • Lyme Neuroborreliosis / drug therapy
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Myelitis, Transverse / diagnosis*
  • Myelitis, Transverse / drug therapy
  • Myelitis, Transverse / etiology
  • Thoracic Vertebrae

Substances

  • Anti-Bacterial Agents