Development of a Pediatric Fertility Preservation Program: A Report From the Pediatric Initiative Network of the Oncofertility Consortium

J Adolesc Health. 2019 May;64(5):563-573. doi: 10.1016/j.jadohealth.2018.10.297. Epub 2019 Jan 14.


Infertility is known to decrease quality of life among adults. In some cases, infertility is caused by medical conditions and/or treatments prescribed in childhood, and using methods to protect or preserve fertility may expand future reproductive possibilities. Structured programs to offer counseling about infertility risk and fertility preservation options are essential in the care of pediatric patients facing fertility-threatening conditions or treatments, yet multiple barriers to program development exist. This report was developed from the institutional experiences of members of the Pediatric Initiative Network of the Oncofertility Consortium, with the intent of providing guidance for health care providers aiming to establish programs at institutions lacking pediatric fertility preservation services. The mechanics of building a fertility preservation program are discussed, including essential team members, target populations, fertility preservation options (both established and experimental), survivorship issues, research opportunities, and ethical considerations. Common barriers to program development and utilization, including low referral rates and financial concerns, are also discussed, and recommendations made for overcoming such barriers.

Keywords: Adolescent; Child; Fertility preservation; Program development; Tissue preservation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adolescent
  • Child
  • Counseling
  • Female
  • Fertility Preservation*
  • Humans
  • Male
  • Medical Oncology*
  • Neoplasms / complications*
  • Pediatrics*
  • Program Development*
  • Quality of Life / psychology
  • Stakeholder Participation