Role of Bile in Infectious Disease: the Gall of 7α-Dehydroxylating Gut Bacteria

Cell Chem Biol. 2019 Jan 17;26(1):1-3. doi: 10.1016/j.chembiol.2018.12.010.


Local antibiotics and quorum sensors produced by gut bacteria regulate microbiota community structure and guard against pathogens. In this issue of Cell Chemical Biology, Kang et al. (2019) guide us through a reciprocal host-antimicrobial interplay that redefines our understanding of Clostridioides (Clostridium) difficile pathogenesis.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Anti-Bacterial Agents
  • Bile
  • Bile Acids and Salts
  • Clostridium difficile*
  • Microbiota*


  • Anti-Bacterial Agents
  • Bile Acids and Salts