Laparoscopic single-anastomosis duodenal-jejunal bypass with sleeve gastrectomy (SADJB-SG): Surgical risk and long-term results

Surg Obes Relat Dis. 2019 Feb;15(2):236-243. doi: 10.1016/j.soard.2018.11.020. Epub 2018 Nov 24.

Abstract

Background: Single-anastomosis duodeno-jejunal bypass with sleeve gastrectomy (SADJB-SG) was developed as a simplified technique of DJB-SG, but long-term data are lacking.

Objective: To report the long-term data of SADJB-SG.

Setting: Tertiary Teaching Hospital.

Methods: A total of 148 SADJB-SG was performed from 2011 to 2016 with mean age of 42.0 ± 10.9-years old (14-71), female 64.9%, and mean body mass index 34.2 ± 5.9 kg/m2. All patients were evaluated and managed under a strict multidisciplinary team approach. A retrospective analysis of a prospective bariatric database and telephone interview of patients who defaulted clinic follow-up at 5-year was conducted.

Results: The mean operating time, intraoperative blood loss, and hospital stay of SADJB-SG were 189.6 ± 32.1 minutes, 43.5 ± 17.9 mL, and 5.0 ± 5.1 days, respectively. The 30-days postoperative major complication occurred in 7(4.7%) patients, all in patients with type 2 diabetes (T2D). At postoperative 1, 2, and 5 years, the mean percentage of total weight loss and excess weight loss of SADJB-SG patients were 25.5%, 22.8%, 22.5%, and 83.9%, 76.1%, 58.6%, respectively. Among 118 patients with T2D, 62 (52.5%) achieved complete remission (hemoglobin A1C <60%) at 1 year and 36.5% at 5 years after surgery. A total of 15 patients needed reoperation at follow-up, due to reflux disease (n = 11), weight regain, and recurrent of T2D (n = 2), ileus (n = 1), and peritonitis (n = 1). Among them, 8 were converted to RYGB and the others remained in same anatomy. At 5 years, the overall revision rate was 12.9% (8/62) and 24.5% (14/57) of the remaining required proton pump inhibitor for reflux symptoms.

Conclusion: Our results show that primary SADJB-SG is a durable primary bariatric procedure with sustained weight loss and a high resolution of T2D at 5 years, but de novo GERD is the major side effect.

Keywords: Duodeno-jejunal bypass; Single anastomosis; Sleeve gastrectomy; T2D.

MeSH terms

  • Adult
  • Anastomosis, Surgical
  • Duodenum / surgery
  • Female
  • Gastrectomy / adverse effects*
  • Gastric Bypass / adverse effects*
  • Humans
  • Jejunum / surgery
  • Laparoscopy / adverse effects*
  • Male
  • Middle Aged
  • Obesity, Morbid / surgery*
  • Operative Time
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome
  • Weight Loss