Ultrasound affects minimal inhibitory concentration of ampicillin against methicillin resistant Staphylococcus aureus USA300

New Microbiol. 2019 Jan;42(1):52-54. Epub 2019 Jan 21.


Antimicrobial resistance is one of the most serious global public health problems. Therefore, novel strategies are needed to counteract bacterial resistance development. The aim of the present study was to enhance the activity of antibiotics to bacteria by using ultrasound. Ultrasound reduced the dosage of ampicillin required to impair bacterial viability.

Keywords: MRSA; ampicillin; antimicrobial; sonowell; ultrasound.

MeSH terms

  • Ampicillin* / administration & dosage
  • Ampicillin* / pharmacology
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / pharmacology
  • Drug Resistance, Bacterial* / radiation effects
  • Methicillin-Resistant Staphylococcus aureus*
  • Microbial Sensitivity Tests
  • Ultrasonography*


  • Anti-Bacterial Agents
  • Ampicillin