Psoriasis Incidence and Lifetime Prevalence: Suggestion for a Higher Mortality Rate in Older Age-classes Among Psoriatic Patients Compared to the General Population in Italy

Acta Derm Venereol. 2019 Apr 1;99(4):400-403. doi: 10.2340/00015555-3130.


Data on the psoriasis incidence and prevalence in the Italian population are limited, and a timely and accurate understanding of the disease epidemiology is needed. This ad hoc study investigated psoriasis incidence and lifetime prevalence in a representative sample (n = 14,705) of the Italian population. Information on lifetime history of skin disorders with details about their onset, duration, and treatment was collected. Psoriasis incidence showed a bimodal distribution pattern, with peaks in age classes characteristic of early-onset (35-44 years) and late-onset (65-74 years) psoriasis. Late-onset psoriasis showed some variations according to the sex, with females being diagnosed earlier than males. Lifetime prevalence of psoriasis was 2.7% (95% confidence interval: 2.5-3.0): it increased to 3.5% at age 60-64 years, then decreased steadily after age 64, to 1.7% at age > 74 years. This decrease, despite a peak in incidence rates, after age 64, may suggest a higher mortality rate among psoriasis patients in older age classes, compared to the general population.

Keywords: age-classes; incidence; lifetime prevalence; mortality; psoriasis.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Prognosis
  • Psoriasis / diagnosis
  • Psoriasis / epidemiology*
  • Psoriasis / mortality
  • Psoriasis / therapy
  • Risk Assessment
  • Risk Factors
  • Sex Distribution
  • Time Factors
  • Young Adult