Basal cell carcinoma with intravascular invasion: A case report and review of the literature

Dermatol Online J. 2018 Oct 15;24(10):13030/qt9q84f22g.


The significance of basal cell carcinoma (BCC) invading the intravascular space is unknown. We report a case of an infiltrative BCC on the scalp that showed evidence of both intravascular and perineural invasion. The tumor locally recurred in the bone marrow space 4.5 years following the initial procedure. Since recurrence and metastasis of BCC can be delayed for many years, we recommend long term follow-up for tumors showing aggressive features.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Blood Vessels / pathology*
  • Bone Marrow / pathology
  • Carcinoma, Basal Cell / pathology*
  • Carcinoma, Basal Cell / surgery
  • Head and Neck Neoplasms / pathology*
  • Head and Neck Neoplasms / surgery
  • Humans
  • Male
  • Middle Aged
  • Mohs Surgery
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local / pathology*
  • Peripheral Nerves / pathology*
  • Scalp / blood supply
  • Scalp / innervation
  • Scalp / pathology*
  • Scalp / surgery
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Skin Transplantation