Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jan 24;23(1):23.
doi: 10.1186/s13054-018-2300-x.

Bronchoalveolar Lavage Fluid Dilution in ICU Patients: What We Should Know and What We Should Do

Free PMC article

Bronchoalveolar Lavage Fluid Dilution in ICU Patients: What We Should Know and What We Should Do

Yuetian Yu et al. Crit Care. .
Free PMC article

Conflict of interest statement

Ethics approval and consent to participate

This study was approved by the ethics committee of Shanghai Jiao Tong University (2016-Clinical-Res-083), and written informed consent was obtained from either the patients or the next of kin.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.


Fig. 1
Fig. 1
a Correlation between PaO2/FiO2 and urea plasma/urea BALF. b Comparison of urea plasma/urea BALF in different PaO2/FiO2 groups. c Correlation between FEV1/FEV1 predicted and urea plasma/urea BALF in patients with COPD. d Comparison of urea plasma/urea BALF in different FEV1/FEV1 predicted groups in patients with COPD. *P <0.05 in each group. Abbreviations: BALF bronchoalveolar lavage fluid, COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume in the first second, FiO2 fractional concentration of inspired oxygen, PaO2 partial pressure of arterial oxygen.

Similar articles

See all similar articles


    1. Ergan B, Nava S. The use of bronchoscopy in critically ill patients: considerations and complications. Expert Rev Respir Med. 2018;12:651–663. doi: 10.1080/17476348.2018.1494576. - DOI - PubMed
    1. Baughman RP. The uncertainties of bronchoalveolar lavage. Eur Respir J. 1997;10:1940–1942. doi: 10.1183/09031936.97.10091940. - DOI - PubMed
    1. Meyer KC, Raghu G, Baughman RP, Brown KK, Costabel U, du Bois RM, et al. An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med. 2012;185:1004–1014. doi: 10.1164/rccm.201202-0320ST. - DOI - PubMed
    1. Roux D, Reignier J, Thiery G, Boyer A, Hayon J, Souweine B, et al. Acquiring procedural skills in ICUs: a prospective multicenter study. Crit Care Med. 2014;42:886–895. doi: 10.1097/CCM.0000000000000049. - DOI - PubMed
    1. Yu Y, Zhu C, Gao Y. Bronchoalveolar lavage fluid galactomannan as a diagnostic biomarker for IPA: still a long way to go. Crit Care. 2016;20:280. doi: 10.1186/s13054-016-1452-9. - DOI - PMC - PubMed