Acute Ethanol Exposure Augments Low-Dose UVB-Mediated Systemic Immunosuppression via Enhanced Production of Platelet-Activating Factor Receptor Agonists

J Invest Dermatol. 2019 Jul;139(7):1619-1622. doi: 10.1016/j.jid.2018.11.034. Epub 2019 Jan 23.

Authors

Jeffrey B Travers¹, Jonathan Weyerbacher², Jesus A Ocana³, Christina Borchers⁴, Christine M Rapp⁴, Ravi P Sahu⁴

Affiliations

¹ Department of Pharmacology and Toxicology, Boonshoft School of Medicine at Wright State University, Dayton, Ohio, USA; The Dayton Veterans Affairs Medical Center, Dayton, Ohio, USA. Electronic address: jeffrey.travers@wright.edu.
² Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indianapolis, Indiana, USA.
³ Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indianapolis, Indiana, USA.
⁴ Department of Pharmacology and Toxicology, Boonshoft School of Medicine at Wright State University, Dayton, Ohio, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Cell Line
Ethanol / administration & dosage*
Ethanol / adverse effects
Humans
Immune Tolerance
Immunosuppression Therapy
Interleukin-8 / metabolism
Keratinocytes / drug effects
Keratinocytes / physiology*
Keratinocytes / radiation effects
Mice
Mice, Knockout
Oxidation-Reduction
Phosphatidylcholines / metabolism*
Platelet Activating Factor / metabolism*
Platelet Membrane Glycoproteins / agonists
Platelet Membrane Glycoproteins / genetics
Platelet Membrane Glycoproteins / metabolism*
Receptors, G-Protein-Coupled / agonists
Receptors, G-Protein-Coupled / genetics
Receptors, G-Protein-Coupled / metabolism*
Ultraviolet Rays / adverse effects

Substances

Interleukin-8
Phosphatidylcholines
Platelet Activating Factor
Platelet Membrane Glycoproteins
Receptors, G-Protein-Coupled
platelet activating factor receptor
Ethanol

Grants and funding