Allergen-specific CD8 + T cells in peanut-allergic individuals

J Allergy Clin Immunol. 2019 May;143(5):1948-1952. doi: 10.1016/j.jaci.2019.01.011. Epub 2019 Jan 22.

Abstract

CD8+ T cells are seldom considered in IgE mediated food allergy; we show that peanut specific CD8+ T cells are increased in peanut allergic human subjects.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Allergens / immunology*
  • Arachis / immunology*
  • CD8-Positive T-Lymphocytes / immunology*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunoglobulin E / immunology
  • Male
  • Middle Aged
  • Peanut Hypersensitivity / immunology*
  • Peptides / immunology*
  • Plant Proteins / immunology*
  • Young Adult

Substances

  • Allergens
  • Peptides
  • Plant Proteins
  • Immunoglobulin E