Vulvar Cancer

Obstet Gynecol Clin North Am. 2019 Mar;46(1):125-135. doi: 10.1016/j.ogc.2018.09.008.


This article reviews the epidemiology, diagnosis, and management of vulvar preinvasive lesions, squamous cell carcinoma, and melanoma. There is an emphasis on sentinel lymph node dissection for early stage disease and advances in chemoradiation for late-stage disease. A brief review of vulvar Paget disease is also included.

Keywords: Chemotherapy; Melanoma; Paget disease; Radiation; Squamous cell carcinoma; Surgery; Vulvar cancer.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / therapy*
  • Chemoradiotherapy*
  • Female
  • Humans
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Melanoma / pathology
  • Melanoma / therapy*
  • Paget Disease, Extramammary / pathology
  • Paget Disease, Extramammary / therapy*
  • Sentinel Lymph Node Biopsy
  • Vulvar Neoplasms / pathology
  • Vulvar Neoplasms / therapy*