Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee

J Rheumatol. 1988 Dec;15(12):1833-40.


Within the context of a double blind randomized controlled parallel trial of 2 nonsteroidal antiinflammatory drugs, we validated WOMAC, a new multidimensional, self-administered health status instrument for patients with osteoarthritis of the hip or knee. The pain, stiffness and physical function subscales fulfil conventional criteria for face, content and construct validity, reliability, responsiveness and relative efficiency. WOMAC is a disease-specific purpose built high performance instrument for evaluative research in osteoarthritis clinical trials.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Clinical Trials as Topic
  • Consumer Behavior
  • Double-Blind Method
  • Evaluation Studies as Topic
  • Female
  • Health Status Indicators*
  • Health Surveys*
  • Hip Joint* / physiopathology
  • Humans
  • Knee Joint* / physiopathology
  • Male
  • Middle Aged
  • Osteoarthritis / drug therapy*
  • Osteoarthritis / physiopathology
  • Pain / drug therapy
  • Piroxicam / analogs & derivatives*
  • Piroxicam / therapeutic use*
  • Random Allocation


  • Piroxicam
  • isoxicam