Bacillus Calmette-Guerin (BCG) endophthalmitis

Retina. 1988;8(3):182-4. doi: 10.1097/00006982-198808030-00006.


A patient who had been treated for metastatic bladder carcinoma with bacillus Calmette-Guerin (BCG) vaccine subsequently developed bilateral visual loss secondary to an infiltrative retinitis and vitreitis. Although assumed to have candida endophthalmitis, vitrectomy demonstrated mycobacterium bovis. The patient was placed on systemic anti-tuberculous therapy, and there was noted to be a reduction in retinal lesions prior to his death. This is the first report in the literature documenting endogenous endophthalmitis after BCG usage.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • BCG Vaccine / adverse effects*
  • Humans
  • Male
  • Mycobacterium Infections / etiology*
  • Mycobacterium bovis / isolation & purification
  • Retinitis / etiology*
  • Urinary Bladder Neoplasms / therapy
  • Vitreous Body / microbiology


  • BCG Vaccine