Influence of prognostic features on the final outcome in rheumatoid arthritis: a review of the literature

Semin Arthritis Rheum. 1988 May;17(4):284-92. doi: 10.1016/0049-0172(88)90013-3.


The literature on prognostic features on the final outcome in RA is reviewed. It is generally agreed that female sex and a positive RF are variables indicating a poor prognosis. Longstanding increased ESR and CRP values, decreased Hb, or the appearance of subcutaneous nodules are indicators of a less favorable clinical course. No conclusions can be drawn regarding other factors due to the incomplete and heterogeneous study designs.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / therapy*
  • Blood Sedimentation
  • C-Reactive Protein / analysis
  • Demography
  • Female
  • HLA Antigens / analysis
  • Hemoglobins / analysis
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Rheumatoid Factor / analysis


  • HLA Antigens
  • Hemoglobins
  • C-Reactive Protein
  • Rheumatoid Factor