Abstract
Fungal corneal infections can be very difficult to treat. An evolving understanding of the pharmacology of the currently available antifungal agents has led to improved medical treatment of the keratomycoses. The pharmacology, pharmacokinetics, spectrum of activity and toxicity of these agents is reviewed and promising new antifungal compounds and modes of treatment are discussed.
MeSH terms
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Antifungal Agents / adverse effects
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Antifungal Agents / pharmacology
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Antifungal Agents / therapeutic use*
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Chemical Phenomena
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Chemistry
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Corneal Diseases / drug therapy*
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Humans
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Imidazoles / therapeutic use
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Molecular Structure
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Mycoses / drug therapy*
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Polyenes / therapeutic use
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Pyrimidines / therapeutic use
Substances
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Antifungal Agents
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Imidazoles
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Polyenes
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Pyrimidines