Predictors of Response to Repetitive Transcranial Magnetic Stimulation in Depression: A Review of Recent Updates

Clin Psychopharmacol Neurosci. 2019 Feb 28;17(1):25-33. doi: 10.9758/cpn.2019.17.1.25.


Transcranial magnetic stimulation (TMS) has been increasingly used in the treatment of various neuropsychiatric disorders including depression over the past two decades. The responses to treatment with TMS are variable as found in the recent studies. Evidences suggest that various factors influence the outcome of depression treated with TMS. Understanding the predictors of response to TMS treatment in depression will guide the clinician in appropriate selection of patients for TMS treatment as well as needful modification in the TMS technique and protocol to have a better clinical outcome. This article comprehensively reviews the factors that predict the outcome of TMS treatment in depression.

Keywords: Depression; Response; Transcranial magnetic stimulation; Treatment outcome.

Publication types

  • Review