Deproteinized bovine bone derived with collagen improves soft and bone tissue outcomes in flapless immediate implant approach and immediate provisionalization: a randomized clinical trial

Clin Oral Investig. 2019 Oct;23(10):3885-3893. doi: 10.1007/s00784-019-02819-x. Epub 2019 Jan 28.

Abstract

Objectives: This study aimed at evaluating soft and hard tissue dimensions after immediate implant placement and immediate temporization with or without alveolar preservation at the maxillary anterior region.

Materials and methods: Twenty-two patients needing maxillary incisor extraction and with the possibility of immediate implant placement were randomly assigned to the following groups: test (n = 11): immediate implant placement + deproteinized bovine bone derived with collagen inserted into the alveolus or control (n = 11): immediate implant placement without biomaterial. All soft tissue measurements were evaluated at baseline, 3 months, and 6 months after implant therapy. Cone beam tomography was performed at baseline and at 6 months after implant placement to evaluate hard tissue dimension.

Results: The test group presented higher height of soft tissue at mesiobuccal and distobuccal sites at 3 months and 6 months when compared to the control group (p < 0.05). Regarding the bone tissue, the test group showed higher buccolingual ridge dimension at 6 months when compared to the control group (p < 0.05).

Conclusions: It can be concluded that the use of deproteinized bovine bone derived with collagen together with immediate dental implants results in better soft and bone tissue outcomes than immediate implants alone.

Clinical relevance: The use of deproteinized bovine bone derived with collagen may enhance the results regarding soft and bone tissue in combination with immediate implant and temporization.

Keywords: Biomaterial; Extraction socket; Grafting; Healing; Immediate implant; Tomographic evaluation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Animals
  • Bone Transplantation*
  • Cattle
  • Collagen*
  • Dental Implants*
  • Humans
  • Immediate Dental Implant Loading*
  • Tooth Extraction
  • Tooth Socket

Substances

  • Dental Implants
  • Collagen