The potential use of mechanism-based enzyme inactivators in medicine

J Enzyme Inhib. 1988;2(2):73-90. doi: 10.3109/14756368809040714.

Abstract

Mechanism-based enzyme inactivator, alanine racemase, S-adenosylhomocysteine hydrolase, D-amino acid aminotransferase, gamma-aminobutyric acid aminotransferase, arginine decarboxylase, aromatase, L-aromatic amino acid decarboxylase, dihydrofolate reductase, dihydroorotate dehydrogenase DNA polymerase I, dopamine beta-hydroxylase, histidine decarboxylase, beta-lactamase, monoamine oxidase, ornithine decarboxylase, serine proteases, testosterone 5 alpha-reductase, thymidylate synthetase, xanthine oxidase.

Publication types

  • Review

MeSH terms

  • Enzyme Inhibitors / therapeutic use*
  • Humans
  • Structure-Activity Relationship

Substances

  • Enzyme Inhibitors