Hemochromatosis - modern condition of the problem

Ter Arkh. 2018 Apr 19;90(3):107-112. doi: 10.26442/terarkh2018903107-112.


The iron overload syndrome can be associated with various acquired states and hereditary factors. Hereditary hemochromatosis is the most common genetic disorder. Without therapeutic intervention the disease can lead to the development of life-threatening complications such as cirrhosis, hepatocellular carcinoma. The article presents data on pathogenesis, diagnosis and treatment of hereditary hemochromatosis. Own clinical observation is given.

Keywords: hereditary haemochromatosis; phlebotomy; treatment.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular / etiology
  • Hemochromatosis* / complications
  • Hemochromatosis* / diagnosis
  • Hemochromatosis* / therapy
  • Humans
  • Liver Cirrhosis / etiology
  • Liver Neoplasms / etiology
  • Syndrome