NSAID-induced enteropathy: the current state of the problem

A A Svistunov; M A Osadchuk; N V Kireeva; A A Hudarova; E E Achkasov

doi:10.26442/terarkh201890895-100

NSAID-induced enteropathy: the current state of the problem

Ter Arkh. 2018 Aug 27;90(8):95-100. doi: 10.26442/terarkh201890895-100.

Authors

A A Svistunov¹, M A Osadchuk¹, N V Kireeva¹, A A Hudarova¹, E E Achkasov¹

Affiliation

¹ I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia.

PMID: 30701943
DOI: 10.26442/terarkh201890895-100

Abstract

The review analyzes the main etiological and pathogenetic mechanisms of the development of NSAID-enteropathy. Particular attention is paid to the role of intestinal microbiota in the manifestation and progression of NSAID-enteropathy. The special role of probiotics in the prevention and treatment of NSAIDs enteropathy is considered.

Keywords: Linex® Forte; NSAID-enteropathy; acetylsalicylic acid; antibiotics; intestinal microbiota; proton pump inhibitors.

Publication types

Review

MeSH terms

Anti-Inflammatory Agents, Non-Steroidal / toxicity*
Gastric Mucosa / drug effects
Gastric Mucosa / microbiology
Gastroenteritis / chemically induced*
Gastroenteritis / microbiology
Gastroenteritis / prevention & control
Humans
Intestinal Mucosa / drug effects
Intestinal Mucosa / microbiology
Microbiota / drug effects
Peptic Ulcer / chemically induced*
Peptic Ulcer / microbiology
Peptic Ulcer / prevention & control
Probiotics / therapeutic use

Substances

Anti-Inflammatory Agents, Non-Steroidal