Optical coherence tomography angiography findings in Behcet patients

Int Ophthalmol. 2019 Oct;39(10):2391-2399. doi: 10.1007/s10792-019-01080-1. Epub 2019 Feb 1.

Abstract

Purpose: Retinal vasculitis and vein occlusions are common causes of serious visual loss in Behçet's disease. We aimed to evaluate the optical coherence tomography angiography (OCTA) findings of Behcet uveitis (BU) patients.

Methods: We evaluated 32 eyes of 16 patients with BU and 30 eyes of 15 healthy controls. Superficial capillary plexus (SCP) and deeper capillary plexuses (DCP) were evaluated using OCTA RTVue XR AVANTI.

Results: On SCP, nonperfusion/hypoperfusion areas (NPA) were seen in 10 eyes, perifoveal capillary arcade disruption (PCAD) was seen in 10 eyes, capillary network disorganization (CND) was seen in 7 eyes and intraretinal cystoid spaces (ICS) were seen in 2 eyes. On DCP, NPA were seen in 13 eyes, PCAD was seen in 11 eyes, CND was seen in 7 eyes and ICS were seen in 4 eyes.

Conclusion: We showed that DCP were affected more than SCP in these patients. In addition, capillary vessel density of BU group was significantly lower than control group.

Keywords: Behçet disease; Optical coherence tomography angiography; Retinal vein occlusion; Uveitis; Vasculitis.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Behcet Syndrome / complications*
  • Female
  • Fluorescein Angiography / methods
  • Humans
  • Male
  • Middle Aged
  • Retinal Vein Occlusion / pathology*
  • Retinal Vessels / pathology
  • Tomography, Optical Coherence / methods
  • Uveitis / pathology*
  • Young Adult