Progressive pseudorheumatoid dysplasia: a report of three cases and a review of radiographic and magnetic resonance imaging findings

Skeletal Radiol. 2019 Sep;48(9):1323-1328. doi: 10.1007/s00256-019-3165-z. Epub 2019 Feb 2.

Abstract

Progressive pseudorheumatoid dysplasia (PPD) is a rare disorder of postnatal skeletal and cartilage development that often presents with similar clinical findings to juvenile idiopathic arthritis. Patients with PPD display findings of progressive cartilage loss and secondary osteoarthritis over serial imaging studies and have an absence of elevation of inflammatory markers. Awareness of the imaging features of PPD on radiographs and magnetic resonance imaging (MRI) may be important for early diagnosis and surveillance of the disease.

Keywords: Juvenile idiopathic arthritis; Magnetic resonance imaging; Pediatric musculoskeletal imaging; Pediatric radiology; Progressive pseudorheumatoid dysplasia; Skeletal dysplasias.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Joint Diseases / congenital*
  • Joint Diseases / diagnostic imaging
  • Magnetic Resonance Imaging / methods*
  • Male
  • Radiography / methods*

Supplementary concepts

  • Arthropathy, progressive pseudorheumatoid, of childhood