Physician attitudes about non-medical switching to biosimilars: results from an online physician survey in the United States

Curr Med Res Opin. 2019 Apr;35(4):611-617. doi: 10.1080/03007995.2019.1571296. Epub 2019 Feb 4.

Abstract

Objective: This study was designed to understand the level of familiarity of US rheumatologists, gastroenterologists and dermatologists with biosimilar therapies, their experience with non-medical switching (switching medications for reasons unrelated to patient health) of patients between biologics and their attitudes towards switching from a biologic to a biosimilar.

Methods: A total of 297 US physicians who currently prescribe biologics for their patients completed a 15-minute online survey. Rheumatologists, dermatologists and gastroenterologists were included.

Results: The majority of physicians (84%) did not want stable patients undergoing a non-medical switch to a biosimilar. While 60% of physicians believed non-medical switching to biosimilars may have a positive impact on healthcare system costs, multiple negative impacts were also expected. A majority of physicians anticipated a negative impact on patient mental health (59%), treatment efficacy (57%), patient safety (53%) and physician office management (60%).

Conclusions: The majority of physicians had concerns regarding non-medical switching to biosimilars and the impact such switching would have on patient care and physician practice.

Keywords: Biologic therapies; attitudes; biosimilar; dermatologists; gastroenterologists; physician; rheumatologists.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Attitude of Health Personnel*
  • Biosimilar Pharmaceuticals / administration & dosage*
  • Biosimilar Pharmaceuticals / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Physicians / statistics & numerical data*
  • Surveys and Questionnaires
  • United States

Substances

  • Biosimilar Pharmaceuticals