A Rare Case of Liver Metastasis from Prostate Cancer Mimicking Hepatocellular Carcinoma on Immunohistochemistry: Role of F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Diagnosis

Raja Senthil; Arun Visakh Ramachandran Nair; Thara Pratap; Vadavattathu Padmanabhan Gangadharan; Pushpa Mahadevan

doi:10.4103/ijnm.IJNM_110_18

A Rare Case of Liver Metastasis from Prostate Cancer Mimicking Hepatocellular Carcinoma on Immunohistochemistry: Role of F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Diagnosis

Indian J Nucl Med. 2019 Jan-Mar;34(1):54-56. doi: 10.4103/ijnm.IJNM_110_18.

Authors

Raja Senthil¹, Arun Visakh Ramachandran Nair¹, Thara Pratap², Vadavattathu Padmanabhan Gangadharan³, Pushpa Mahadevan⁴

Affiliations

¹ Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi, Kerala, India.
² Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India.
³ Department of Medical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India.
⁴ Department of Pathology, VPS Lakeshore Hospital, Kochi, Kerala, India.

Abstract

We present a case with space-occupying lesion in cirrhotic liver, diagnosed as hepatocellular carcinoma on immunohistochemistry, who underwent F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) and showed FDG-avid lesions in liver as well as in the prostate. These findings guided in establishing the diagnosis of prostate cancer, metastasizing to liver by performing additional immunohistochemical markers. PET/CT was also useful in identifying coexisting non-Hodgkin's lymphoma.

Keywords: F-18 fluorodeoxyglucose positron emission tomography/computed tomography; P504s; hepatocellular carcinoma; hepatocyte antibody stain; prostate cancer.

Publication types

Case Reports