Phytochemical profile of genotypes of Euterpe edulis Martius - Juçara palm fruits

Food Res Int. 2019 Feb;116:985-993. doi: 10.1016/j.foodres.2018.09.036. Epub 2018 Sep 13.

Abstract

Juçara fruit (Euterpe edulis) has received attention due to its similarities to Euterpe oleracea (Açaí). The aim of this study was to evaluate the cytotoxicity, bioactive compounds, antioxidant capacities and chemopreventive activities of the fruit pulps of six populations of E. edulis (J1-J6) and one population of E. espiritosantense from different ecological regions. ESI(-)-FT-ICR-MS was used to evaluate the pulp composition. The varieties J1 and J4 presented higher polyphenol contents, while J2 and J5 showed higher anthocyanin contents. ESI-FT-ICR MS identified cyanidin-3-rutinoside (J1, J2, J3, J4, J5, J7), protocatechuic acid, methylhydroxybenzoate hexoside and rutin (J1 to J7) and malvidin-glicoside (J2 to J5). The J2, J3, J4, J5 and J6 samples inhibited inducible nitric oxide synthase (iNOS). The chemoprevention biomarker quinone reductase was significantly induced by J6. Pulp from plants J3, J4, J6 and J7 significantly reduced the inflammatory cytokine TNF-α, and J6 was selected as having the most potential for cultivation and consumption.

Keywords: Antioxidant; Chemopreventive effect; Juçara; Sustainability.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology*
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Benzothiazoles / chemistry
  • Cell Line, Tumor
  • Cytokines / metabolism
  • Euterpe / chemistry*
  • Euterpe / genetics
  • Fruit / chemistry*
  • Fruit / genetics
  • Genotype
  • Humans
  • Macrophages / drug effects
  • Macrophages / enzymology
  • Mice
  • NF-kappa B / metabolism
  • Nitric Oxide / metabolism
  • Nitric Oxide Synthase Type II / antagonists & inhibitors
  • Nitric Oxide Synthase Type II / metabolism
  • Phytochemicals / isolation & purification
  • Phytochemicals / pharmacology*
  • RAW 264.7 Cells
  • Sulfonic Acids / chemistry

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Benzothiazoles
  • Cytokines
  • NF-kappa B
  • Phytochemicals
  • Sulfonic Acids
  • 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
  • Nitric Oxide
  • Nitric Oxide Synthase Type II
  • Nos2 protein, mouse