Optical coherence tomography and optical coherence tomography angiography in uveitis: A review

Clin Exp Ophthalmol. 2019 Apr;47(3):357-371. doi: 10.1111/ceo.13470. Epub 2019 Mar 3.


Optical coherence tomography (OCT) has dramatically changed the understanding and management of uveitis and other ocular conditions. Currently, OCT angiography (OCTA) combines structural information with the visualization of blood flow within the imaged area. The aim of this review is to present the basic principles of OCT and OCTA interpretation and to investigate the role of these imaging techniques in the diagnosis and management of uveitis. Common complications of intraocular inflammation such as macular oedema and inflammatory choroidal neovascularization are often diagnosed and followed with OCT/OCTA scans. However, uveitis specialists can obtain much more information from tomographic scans. This review provides a comprehensive description of typical OCT/OCTA findings characterizing different ocular structures in uveitis, proceeding from the cornea to the choroid. A careful interpretation of OCT/OCTA images can help in the differential diagnosis, the prediction of clinical outcomes, and the follow-up of patients with uveitis.

Keywords: optical coherence tomography; optical coherence tomography angiography; uveitis.

Publication types

  • Review

MeSH terms

  • Choroidal Neovascularization / diagnosis
  • Choroidal Neovascularization / etiology
  • Fluorescein Angiography / methods*
  • Humans
  • Macular Edema / diagnosis
  • Macular Edema / etiology
  • Tomography, Optical Coherence / methods*
  • Uveitis / complications
  • Uveitis / diagnosis*