In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.


Urethritis is inflammation of the urethra and is a lower urinary tract infection. The urethra is a fibromuscular tube through which urine exits the body in both males and females and semen in males. Urethritis has a strong association with sexually transmitted infections (STIs). Urethritis is characterized as gonococcal or nongonococcal infections. Neisseria gonorrhea and Chlamydia trachomatis are the most common causative organisms of STIs. The most common symptom of urethritis is urethral discharge.

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