Background and purpose: Sufficient evidence exists recommending the use of honey in the management of wounds. Studies revealed that the healing effect of honey could be classified by its antibacterial and anti-inflammatory properties of its components. Since surgical extraction of impacted molars is one of the most common operations in the oral cavity and the postoperative pain disturbing the patient may reduce the quality of health service, this study aimed to assess the analgesic potential of Manuka honey application into the extraction socket of impacted mandibular third molars.
Methods: This randomized split-mouth controlled study included 33 patients undergoing impacted bilateral lower third molars surgery under local anesthesia (n = 66). Randomization was carried out by coin flipping. One of the two impacted third molars was assigned to treatment group (Manuka honey applied just before suturing), other side to control group (nothing applied). Postsurgical pain was evaluated using visual analogue scale (VAS) of faces 7 days after extraction. The total analgesic dose used was also evaluated.
Results: In treatment group, postoperative VAS scores were significantly lower compared to that in control group regarding first and second days postoperatively (P < 0.05). Total analgesic intake in the control group was significantly higher (P = 0.0001).
Conclusion: This study demonstrated that intrasocket application of Manuka honey after surgical extraction of impacted lower third molar is an effective method for reducing acute postsurgical pain.
Keywords: Impaction; Manuka honey; Pain; Postoperative analgesia; Third molar surgery.
Conflict of interest statement
The authors declare that they have no conflict of interest.All procedures performed in studies involving human participants were in accordance with the ethical standards of institutional and national research committee and with the 1964 Declaration of Helsinki and its amendments.Informed consent was obtained from all individual participants included in the study.
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Local Interventions for the Management of Alveolar Osteitis (Dry Socket)B Daly et al. Cochrane Database Syst Rev 12, CD006968. PMID 23235637. - ReviewMost tooth extractions are undertaken by dentists for a variety of reasons, however, all but three studies included in the present review included participants undergoing …
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The Influence of Intra-Alveolar Application of Honey Versus Chlorhexidine Rinse on the Incidence of Alveolar Osteitis Following Molar Teeth Extraction. A Randomized Clinical Parallel TrialN Abu-Mostafa et al. J Clin Exp Dent 11 (10), e871-e876. PMID 31636855.The application of Manuka honey in the extraction socket directly after extraction and on day 3 has been found to be insignificantly less efficient in the prevention of A …