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, 14 (4), 439-443
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Multimodality Appearance of Multiple Endocrine Neoplasia Type 1: A Case Report

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Case Reports

Multimodality Appearance of Multiple Endocrine Neoplasia Type 1: A Case Report

John Monge et al. Radiol Case Rep.

Abstract

Multiple endocrine neoplasia type 1 is a rare autosomal dominant disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary, and enteropancreatic endocrine cells. We present the clinical details of a patient with diarrhea, nephrolithiasis, erectile dysfunction, and new onset abdominal pain, as well as a discussion of the etiology, pathophysiology, and classical imaging findings of this condition.

Keywords: Multiple endocrine neoplasia type 1.

Figures

Fig. 1
Fig. 1
Sagittal (a) and coronal (b), fat saturated T1 postcontrast MRI images demonstrating a well-defined, enhancing mass in the tail of the left epididymis, suggestive of an adenomatoid tumor.
Fig. 2
Fig. 2
Whole body (a), axial (b), and SPECT/CT (c) images of an Indium-111 pentetriotide scan emphasizing a 2.5-cm pentetriotide avid neoplasm in the fourth portion of the duodenum.
Fig. 3
Fig. 3
Sequential pinhole images from a sestamibi scan show an abnormal focus of tracer uptake along the inferior right thyroid lobe, which retains uptake on delayed images. These findings are compatible with a parathyroid adenoma.
Fig. 4
Fig. 4
Sagittal (a) and coronal (b), T1-weighted postcontrast MRI images through the pituitary gland demonstrating an enhancing sellar/suprasellar mass with apparent extension into the medial aspect of the left cavernous sinus, consistent with a pituitary adenoma.
Fig. 5
Fig. 5
Contrast-enhanced CT images through the abdomen highlighting several well-circumscribed enhancing lesions. (a) Arterial phase image with lesion in the descending duodenum. (b) Portal venous phase image with lesion in the distal transverse duodenum. (c) Arterial phase image with pancreatic tail lesions.

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