Adductor Canal Nerve Versus Femoral Nerve Blockade for Pain Control and Quadriceps Function Following Anterior Cruciate Ligament Reconstruction With Patellar Tendon Autograft: A Prospective Randomized Trial

Arthroscopy. 2019 Mar;35(3):921-929. doi: 10.1016/j.arthro.2018.10.149. Epub 2019 Feb 4.

Abstract

Purpose: To compare femoral nerve blockade (FNB) versus adductor canal nerve blockade (ACB) for postoperative pain control and quadriceps muscle function in patients undergoing anterior cruciate ligament (ACL) reconstruction with patellar tendon autograft.

Methods: A randomized therapeutic trial of 90 patients undergoing ACL reconstruction with patellar tendon autograft was conducted comparing ACB versus FNB at 24 hours, 2 and 4 weeks, and 6 months postsurgery. Early outcome measures included average pain score and morphine equivalent units (milligrams) consumed, quadriceps surface electromyography, straight leg raise, and ability to ambulate without assistive devices. The 6-month outcome measures included knee range of motion (ROM), isokinetic knee extension peak torque, single-leg squat, and single-leg hop performance. Complications were recorded throughout the study for the development of anterior knee pain, knee extension ROM loss, deep vein thrombosis, and graft failure. Mixed-model analysis of variance and Mann-Whitney U tests were performed using an alpha of .05.

Results: Quadriceps surface electromyography deficits were higher for FNB at 24 hours (P < .001) and 2 weeks (P < .001) when compared with the ACB group. There were no between-groups difference for subjective pain (P = .793) or morphine consumption (P = .358) within the first 24 hours of surgery. A higher percentage of patients in the ACB group met the full ambulation criteria at 4 weeks compared with the FNB group (100% vs 84.2%, P < .001). No between-group differences were observed at 6 months; however, the rate of knee extension ROM loss was higher for the FNB group versus the ACB group (21.1% vs 5.0%, P = .026), respectively.

Conclusions: ACB was as effective as FNB at providing pain control while eliciting fewer quadriceps muscle activation deficits and fewer postoperative complications. Based on previous evidence and the results of this study, we recommend the use of ACB over FNB for the analgesic management of patients undergoing ACL reconstruction with patellar tendon autograft.

Level of evidence: Level I, prospective randomized controlled trial.

Trial registration: ClinicalTrials.gov NCT03704376.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Analgesics
  • Analysis of Variance
  • Anesthesia, Conduction / methods
  • Anterior Cruciate Ligament Reconstruction* / methods
  • Autografts
  • Clonidine / therapeutic use
  • Electromyography
  • Female
  • Femoral Nerve*
  • Humans
  • Knee Joint / surgery
  • Male
  • Middle Aged
  • Nerve Block / methods*
  • Pain Management / methods*
  • Pain, Postoperative / etiology
  • Pain, Postoperative / prevention & control*
  • Patellar Ligament / transplantation*
  • Prospective Studies
  • Quadriceps Muscle / physiopathology*
  • Range of Motion, Articular / physiology
  • Ropivacaine / therapeutic use*
  • Transplantation, Autologous / adverse effects
  • Young Adult

Substances

  • Analgesics
  • Ropivacaine
  • Clonidine

Associated data

  • ClinicalTrials.gov/NCT03704376