The Roswell Park Memorial Institute and Gastrointestinal Tumor Study Group phase III experience with the modulation of 5-fluorouracil by leucovorin in metastatic colorectal adenocarcinoma

Adv Exp Med Biol. 1988;244:143-55. doi: 10.1007/978-1-4684-5607-3_15.
No abstract available

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Clinical Trials as Topic
  • Colorectal Neoplasms / drug therapy*
  • Diarrhea / chemically induced
  • Fluorouracil / administration & dosage
  • Humans
  • Leucovorin / administration & dosage
  • Leukopenia / chemically induced
  • Methotrexate / administration & dosage
  • Random Allocation
  • Thrombocytopenia / chemically induced

Substances

  • Leucovorin
  • Fluorouracil
  • Methotrexate

Supplementary concepts

  • Fu-CF protocol