Gastrointestinal function in dementia with Lewy bodies: a comparison with Parkinson disease

Clin Auton Res. 2019 Dec;29(6):633-638. doi: 10.1007/s10286-019-00597-w. Epub 2019 Feb 11.

Abstract

Purpose: To investigate gastrointestinal function in dementia with Lewy bodies and Parkinson disease.

Methods: We examined gastric emptying and colonic transit time in 19 dementia with Lewy bodies and 46 Parkinson disease patients.

Results: Gastric emptying was longer in dementia with Lewy bodies than in Parkinson disease (p = 0.014). Colonic transit time tended to be longer in dementia with Lewy bodies than in Parkinson disease. There was no relationship between gastric emptying and colonic transit time, nor between gastric emptying, colonic transit time and age.

Conclusion: Gastric emptying was prolonged in dementia with Lewy bodies compared to Parkinson disease.

Keywords: Colonic transit time; Constipation; Dementia with Lewy bodies; Gastric emptying; Parkinson disease.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Female
  • Gastric Emptying / physiology*
  • Gastrointestinal Transit / physiology*
  • Humans
  • Lewy Body Disease / physiopathology*
  • Male
  • Parkinson Disease / physiopathology*