The Role of Biomarkers in Psychiatry

doi:10.1007/978-3-030-05542-4_7

Review

. 2019:1118:135-162.

doi: 10.1007/978-3-030-05542-4_7.

The Role of Biomarkers in Psychiatry

Madia Lozupone¹, Maddalena La Montagna², Francesca D'Urso², Antonio Daniele^{3

4}, Antonio Greco⁵, Davide Seripa⁵, Giancarlo Logroscino^{1

6}, Antonello Bellomo², Francesco Panza^{7

8

9}

Affiliations

¹ Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
² Psychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
³ Institute of Neurology, Catholic University of Sacred Heart, Rome, Italy.
⁴ Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
⁵ Geriatric Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, Foggia, Italy.
⁶ Department of Clinical Research in Neurology, University of Bari Aldo Moro, Lecce, Italy.
⁷ Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy. geriat.dot@geriatria.uniba.it.
⁸ Geriatric Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, Foggia, Italy. geriat.dot@geriatria.uniba.it.
⁹ Department of Clinical Research in Neurology, University of Bari Aldo Moro, Lecce, Italy. geriat.dot@geriatria.uniba.it.

PMID: 30747421
DOI: 10.1007/978-3-030-05542-4_7

Review

The Role of Biomarkers in Psychiatry

Madia Lozupone et al. Adv Exp Med Biol. 2019.

. 2019:1118:135-162.

doi: 10.1007/978-3-030-05542-4_7.

Authors

Madia Lozupone¹, Maddalena La Montagna², Francesca D'Urso², Antonio Daniele^{3

4}, Antonio Greco⁵, Davide Seripa⁵, Giancarlo Logroscino^{1

6}, Antonello Bellomo², Francesco Panza^{7

8

9}

Affiliations

¹ Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
² Psychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
³ Institute of Neurology, Catholic University of Sacred Heart, Rome, Italy.
⁴ Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
⁵ Geriatric Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, Foggia, Italy.
⁶ Department of Clinical Research in Neurology, University of Bari Aldo Moro, Lecce, Italy.
⁷ Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy. geriat.dot@geriatria.uniba.it.
⁸ Geriatric Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, Foggia, Italy. geriat.dot@geriatria.uniba.it.
⁹ Department of Clinical Research in Neurology, University of Bari Aldo Moro, Lecce, Italy. geriat.dot@geriatria.uniba.it.

PMID: 30747421
DOI: 10.1007/978-3-030-05542-4_7

Abstract

Psychiatric illnesses are cognitive and behavioral disorders of the brain. At present, psychiatric diagnosis is based on DSM-5 criteria. Even if endophenotype specificity for psychiatric disorders is discussed, it is difficult to study and identify psychiatric biomarkers to support diagnosis, prognosis, or clinical response to treatment. This chapter investigates the innovative biomarkers of psychiatric diseases for diagnosis and personalized treatment, in particular post-genomic data and proteomic analyses.

Keywords: Biomarker; Bipolar disorder; Depressive disorder; Epigenetics; Lifestyle; Microbiota; Post-genomic diagnostics; Proteomics; Psychiatric disease; Schizophrenia.

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The Role of Biomarkers in Psychiatry

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