The effectiveness of Hemopatch™ in preventing postoperative distal pancreatectomy fistulas

Expert Rev Med Devices. 2019 Mar;16(3):253-256. doi: 10.1080/17434440.2019.1582328. Epub 2019 Feb 26.

Abstract

Objectives: Postoperative fistula after distal pancreatectomy (DP) is still a significant complication, although many tools and tips have been utilized to try to reduce its elevated frequency. This paper focuses on the role of a sealing hemostatic device, Hemopatch™, to prevent postoperative pancreatic fistula (POPF) after DP.

Methods: Retrospectively we divided our sampling of 57 patients submitted to DP into two groups according to the availability of the device: 18 patients without Hemopatch™ and 39 patients using Hemopatch™.

Results: Significant difference was observed in leak occurrence (p < 0.05). No significant association was observed between the number of blood transfusions, the frequency of postoperative complications, associated splenectomy and POPF.

Conclusion: This is a preliminary study and the first focused on the prevention of POPF after DP using Hemopatch™. Thanks to its double function of hemostasis and sealant, Hemopatch™ can be taken into consideration as an efficacy tool to prevent pancreatic POPF.

Keywords: Pancreatic fistula; distal pancreatectomy; hemopatch; pancreatic surgery; postoperative fistula.

MeSH terms

  • Adult
  • Aged
  • Confounding Factors, Epidemiologic
  • Endpoint Determination
  • Female
  • Hemostatic Techniques / instrumentation*
  • Humans
  • Male
  • Middle Aged
  • Pancreatectomy / adverse effects*
  • Pancreatic Fistula / etiology*
  • Pancreatic Fistula / prevention & control*
  • Postoperative Complications / etiology*
  • Postoperative Complications / prevention & control*
  • Retrospective Studies
  • Treatment Outcome