Allergic contact dermatitis caused by isobornyl acrylate when using the FreeStyle ® Libre

J Diabetes Investig. 2019 Sep;10(5):1382-1384. doi: 10.1111/jdi.13023. Epub 2019 Mar 18.

Abstract

We present the case of an 8-year-old girl with type 1 diabetes who developed severe allergic contact dermatitis by using FreeStyle® Libre. A patch test was carried out using a piece of the adhesive part of the sensor of the FreeStyle® Libre, and subsequently by using the potential contact allergens in the sensor, isobornyl acrylate. She reacted positively to the adhesive part of the sensor, and also reacted positively to isobornyl acrylate with three different concentrations, 0.1%, 0.05% and 0.01%, over 48-h, 72-h and 7-day periods. The FreeStyle® Libre is a useful and less invasive device that can be used for continuous glucose monitoring in patients with diabetes. In contrast to the remarkable advantages, allergic contact dermatitis caused by isobornyl acrylate in the adhesive part of FreeStyle® Libre is one of the potential adverse events.

Keywords: Adverse event; FreeStyle® Libre; Isobornyl acrylate.

Publication types

  • Case Reports

MeSH terms

  • Acrylates / adverse effects*
  • Blood Glucose Self-Monitoring / adverse effects*
  • Blood Glucose Self-Monitoring / instrumentation
  • Camphanes / adverse effects*
  • Child
  • Dermatitis, Allergic Contact / etiology*
  • Diabetes Mellitus, Type 1 / blood*
  • Diabetes Mellitus, Type 1 / drug therapy
  • Female
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Prognosis

Substances

  • Acrylates
  • Camphanes
  • Hypoglycemic Agents
  • isobornyl acrylate