Sugar and Fatty Acids Ack-celerate Prophage Induction

Cell Host Microbe. 2019 Feb 13;25(2):175-176. doi: 10.1016/j.chom.2019.01.012.

Abstract

Intestinal cues driving prophage induction in the microbiota are largely unknown. In this issue of Cell Host & Microbe, Oh et al. (2018) reveal that dietary fructose- and microbiota-derived short-chain fatty acids promote AckA-mediated acetic acid biosynthesis, triggering a stress response that facilities phage production.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Bacteriophages*
  • Fatty Acids
  • Fatty Acids, Volatile
  • Fructose
  • Lactobacillus reuteri*
  • Microbiota*
  • Sugars
  • Virus Activation

Substances

  • Fatty Acids
  • Fatty Acids, Volatile
  • Sugars
  • Fructose