OMERACT Hip Inflammation Magnetic Resonance Imaging Scoring System (HIMRISS) Assessment in Longitudinal Study

Jacob L Jaremko; Robert G W Lambert; Susanne J Pedersen; Ulrich Weber; Duncan Lindsay; Zeid Al-Ani; Kieran Steer; Marcus Pianta; Stephanie Wichuk; Walter P Maksymowych

doi:10.3899/jrheum.181043

OMERACT Hip Inflammation Magnetic Resonance Imaging Scoring System (HIMRISS) Assessment in Longitudinal Study

J Rheumatol. 2019 Sep;46(9):1239-1242. doi: 10.3899/jrheum.181043. Epub 2019 Feb 15.

Authors

Jacob L Jaremko^{1

2}, Robert G W Lambert^{3

4}, Susanne J Pedersen^{3

4}, Ulrich Weber^{3

4}, Duncan Lindsay^{3

4}, Zeid Al-Ani^{3

4}, Kieran Steer^{3

4}, Marcus Pianta^{3

4}, Stephanie Wichuk^{3

4}, Walter P Maksymowych^{3

4}

Affiliations

¹ From the Department of Radiology and Diagnostic Imaging, University of Alberta; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen; King Christian 10th Hospital for Rheumatic Diseases, Gråsten; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark; St. Vincent's Hospital, Melbourne, Australia. jjaremko@ualberta.ca.
² J.L. Jaremko, MD, PhD, FRCPC, Department of Radiology and Diagnostic Imaging, University of Alberta; R.G. Lambert, MB, FRCPC, Department of Radiology and Diagnostic Imaging, University of Alberta; S.J. Pedersen, MD, Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases; U. Weber, MD, Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, and Hospital of Southern Jutland, University Hospital of the Region of Southern Denmark, and Department of Regional Health Research, University of Southern Denmark; D. Lindsay, MD, Department of Radiology and Diagnostic Imaging, University of Alberta; Z. Al-Ani, MD, Department of Radiology and Diagnostic Imaging, University of Alberta; K. Steer, BSc, Department of Radiology and Diagnostic Imaging, University of Alberta; M. Pianta, MD, St. Vincent's Hospital; S. Wichuk, BSc, Department of Medicine, University of Alberta; W.P. Maksymowych, MB ChB, FRCP(C), FACP, Department of Medicine, University of Alberta. jjaremko@ualberta.ca.
³ From the Department of Radiology and Diagnostic Imaging, University of Alberta; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen; King Christian 10th Hospital for Rheumatic Diseases, Gråsten; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark; St. Vincent's Hospital, Melbourne, Australia.
⁴ J.L. Jaremko, MD, PhD, FRCPC, Department of Radiology and Diagnostic Imaging, University of Alberta; R.G. Lambert, MB, FRCPC, Department of Radiology and Diagnostic Imaging, University of Alberta; S.J. Pedersen, MD, Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases; U. Weber, MD, Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, and Hospital of Southern Jutland, University Hospital of the Region of Southern Denmark, and Department of Regional Health Research, University of Southern Denmark; D. Lindsay, MD, Department of Radiology and Diagnostic Imaging, University of Alberta; Z. Al-Ani, MD, Department of Radiology and Diagnostic Imaging, University of Alberta; K. Steer, BSc, Department of Radiology and Diagnostic Imaging, University of Alberta; M. Pianta, MD, St. Vincent's Hospital; S. Wichuk, BSc, Department of Medicine, University of Alberta; W.P. Maksymowych, MB ChB, FRCP(C), FACP, Department of Medicine, University of Alberta.

PMID: 30770513
DOI: 10.3899/jrheum.181043

Abstract

Objective: To assess reliability, feasibility, and responsiveness of Hip Inflammation Magnetic resonance imaging Scoring System (HIMRISS) for bone marrow lesions (BML) in hip osteoarthritis (OA).

Methods: HIMRISS was scored by 8 readers in 360 hips of 90 patients imaged pre/post-hip steroid injection. Pre-scoring, new readers trained online to achieve intraclass correlation coefficient (ICC) > 0.80 versus experts.

Results: HIMRISS reliability was excellent for BML status (ICC 0.83-0.92). Despite small changes post-injection, reliability of BML change scores was high in femur (0.76-0.81) and moderate in acetabulum (0.42-0.56).

Conclusion: HIMRISS should be a priority for further assessment of hip BML in OA, and evaluated for use in other arthropathies.

Keywords: BONE MARROW; HIP JOINT; IMAGING; OMERACT; OSTEOARTHRITIS; SCORING METHODS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bone Marrow / diagnostic imaging*
Hip Joint / diagnostic imaging*
Humans
Inflammation / diagnostic imaging
Magnetic Resonance Imaging*
Severity of Illness Index