CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys

Cell Res. 2019 Apr;29(4):334-336. doi: 10.1038/s41422-019-0142-y. Epub 2019 Feb 15.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CRISPR-Cas Systems
  • Gene Editing
  • Macaca mulatta / embryology
  • Neurodegenerative Diseases / metabolism*
  • Protein Kinases / genetics*
  • Protein Kinases / metabolism*

Substances

  • Protein Kinases
  • PTEN-induced putative kinase