High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors

Leuk Lymphoma. 2019 Sep;60(9):2324-2327. doi: 10.1080/10428194.2019.1577414. Epub 2019 Feb 18.

Authors

Louis Perol^{1

2}, Eric Grignano^{1

2}, Adrien Contejean^{1

2}, Lauris Gastaud³, Marielle Legoff^{1

2}, Patricia Franchi^{1

2}, Bénédicte Deau-Fischer^{1

2}, Lise Willems^{1

2}, Didier Bouscary^{1

2}, Jerome Tamburini^{1

2}

Affiliations

¹ Hematology Department, Cochin Hospital , Paris , France.
² Paris Descartes University , Paris , France.
³ Hematology Department, Antoine Lacassagne Cancer Center , Nice, France.

PMID: 30773115
DOI: 10.1080/10428194.2019.1577414

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Blood Transfusion / ethics*
Cyclophosphamide / administration & dosage
Cyclophosphamide / adverse effects
Dose-Response Relationship, Drug
Doxorubicin / administration & dosage
Doxorubicin / adverse effects
Female
Hematinics / administration & dosage*
Humans
Jehovah's Witnesses*
Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
Prednisone / administration & dosage
Prednisone / adverse effects
Treatment Outcome
Vincristine / administration & dosage
Vincristine / adverse effects

Substances

Hematinics
Vincristine
Doxorubicin
Cyclophosphamide
Prednisone

Supplementary concepts

CHOP protocol