Myeloablative single-unit cord blood transplantation overcomes the negative prognostic impact of FLT3-ITD in adult acute myeloid leukemia

Leuk Lymphoma. 2019 Sep;60(9):2320-2323. doi: 10.1080/10428194.2019.1579325. Epub 2019 Feb 18.

Authors

Takaaki Konuma¹, Seiko Kato¹, Maki Oiwa-Monna¹, Mai Mizusawa¹, Masamichi Isobe¹, Kazuaki Yokoyama¹, Satoshi Takahashi¹, Arinobu Tojo¹

Affiliation

¹ Department of Hematology/Oncology, The Institute of Medical Science The University of Tokyo , Tokyo , Japan.

PMID: 30775946
DOI: 10.1080/10428194.2019.1579325

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Adult
Aged
Antineoplastic Agents
Cord Blood Stem Cell Transplantation*
Disease-Free Survival
Female
Follow-Up Studies
Gene Duplication
Humans
Kaplan-Meier Estimate
Leukemia, Myeloid, Acute / genetics
Leukemia, Myeloid, Acute / mortality
Leukemia, Myeloid, Acute / therapy*
Male
Middle Aged
Myeloablative Agonists / administration & dosage*
Prognosis
Retrospective Studies
Tandem Repeat Sequences / genetics
Transplantation Conditioning / methods*
Whole-Body Irradiation
Young Adult
fms-Like Tyrosine Kinase 3 / genetics*

Substances

Antineoplastic Agents
Myeloablative Agonists
FLT3 protein, human
fms-Like Tyrosine Kinase 3