Dental-craniofacial Manifestation and Treatment of Rare Diseases

Int J Oral Sci. 2019 Feb 20;11(1):9. doi: 10.1038/s41368-018-0041-y.


Rare diseases are usually genetic, chronic and incurable disorders with a relatively low incidence. Developments in the diagnosis and management of rare diseases have been relatively slow due to a lack of sufficient profit motivation and market to attract research by companies. However, due to the attention of government and society as well as economic development, rare diseases have been gradually become an increasing concern. As several dental-craniofacial manifestations are associated with rare diseases, we summarize them in this study to help dentists and oral maxillofacial surgeons provide an early diagnosis and subsequent management for patients with these rare diseases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Craniofacial Abnormalities*
  • Humans
  • Rare Diseases*