Molecular Mechanisms of Plant Regeneration

Annu Rev Plant Biol. 2019 Apr 29;70:377-406. doi: 10.1146/annurev-arplant-050718-100434. Epub 2019 Feb 20.

Abstract

Plants reprogram somatic cells following injury and regenerate new tissues and organs. Upon perception of inductive cues, somatic cells often dedifferentiate, proliferate, and acquire new fates to repair damaged tissues or develop new organs from wound sites. Wound stress activates transcriptional cascades to promote cell fate reprogramming and initiate new developmental programs. Wounding also modulates endogenous hormonal responses by triggering their biosynthesis and/or directional transport. Auxin and cytokinin play pivotal roles in determining cell fates in regenerating tissues and organs. Exogenous application of these plant hormones enhances regenerative responses in vitro by facilitating the activation of specific developmental programs. Many reprogramming regulators are epigenetically silenced during normal development but are activated by wound stress and/or hormonal cues.

Keywords: cell dedifferentiation; cell proliferation; cellular reprogramming; epigenetic regulation; plant hormones; wound stress.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis*
  • Cytokinins
  • Indoleacetic Acids
  • Plant Growth Regulators
  • Regeneration

Substances

  • Cytokinins
  • Indoleacetic Acids
  • Plant Growth Regulators