Cancer stem cells: here, there, and everywhere

Mol Cell Oncol. 2018 Dec 4;6(1):1540235. doi: 10.1080/23723556.2018.1540235. eCollection 2019.


By using marker-free lineage tracing in combination with quantitative analysis, we recently revealed cancer stem cell functionality in established human colon cancer is not intrinsically defined, but fully spatiotemporally regulated.

Keywords: Colon cancer; Osteopontin (OPN, Spp1); cancer stem cells; stem cell dynamics; tumor growth.