Changes in Gut Microbiota and Hormones After Bariatric Surgery: a Bench-to-Bedside Review

Obes Surg. 2019 May;29(5):1663-1674. doi: 10.1007/s11695-019-03779-7.


Overweight and obesity are among the most prevalent non-communicable diseases which are generally treated successfully by bariatric or sleeve surgery. There are evidences affirming that sleeve surgery can manipulate the pH of the stomach and interact with the metabolism of fatty acids, carbohydrates, and bile acid transfer, leading to the overgrowth of gut microbiota. Therefore, this study aims to review the changes in gut microbiota and hormones after bariatric surgery.

Keywords: Gastric sleeve surgery; Gut microbiota; Obesity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Bariatric Surgery*
  • Bile Acids and Salts / metabolism
  • Gastrointestinal Microbiome*
  • Humans
  • Hydrogen-Ion Concentration
  • Inflammation / metabolism
  • Obesity / metabolism
  • Postoperative Complications
  • Stomach / chemistry


  • Anti-Bacterial Agents
  • Bile Acids and Salts