Minimal change disease and Kimura's disease responding to tacrolimus therapy

Saudi J Kidney Dis Transpl. 2019 Jan-Feb;30(1):254-257.

Abstract

Kimura's disease (KD) usually presents with a subcutaneous swelling and associated lymphadenopathy in the periauricular area. KD has a tendency to involve the kidneys. Proteinuria is reported in 12%-16% of cases, and around 60%-70% of them develop nephrotic range proteinuria. We are reporting a case of KD which developed around 12 years later in a patient of biopsy-proven steroid responsive minimal change disease. Recurrent swellings of KD and subnephrotic range proteinuria responded to low-dose tacrolimus therapy (0.05 mg/kg).

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Angiolymphoid Hyperplasia with Eosinophilia* / complications
  • Angiolymphoid Hyperplasia with Eosinophilia* / drug therapy
  • Edema
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Nephrosis, Lipoid* / complications
  • Nephrosis, Lipoid* / drug therapy
  • Proteinuria
  • Tacrolimus / therapeutic use*

Substances

  • Immunosuppressive Agents
  • Tacrolimus