Improving Reproducibility in Synthetic Biology

Front Bioeng Biotechnol. 2019 Feb 11;7:18. doi: 10.3389/fbioe.2019.00018. eCollection 2019.


Synthetic biology holds great promise to deliver transformative technologies to the world in the coming years. However, several challenges still remain to be addressed before it can deliver on its promises. One of the most important issues to address is the lack of reproducibility within research of the life sciences. This problem is beginning to be recognised by the community and solutions are being developed to tackle the problem. The recent emergence of automated facilities that are open for use by researchers (such as biofoundries and cloud labs) may be one of the ways that synthetic biologists can improve the quality and reproducibility of their work. In this perspective article, we outline these and some of the other technologies that are currently being developed which we believe may help to transform how synthetic biologists approach their research activities.

Keywords: automation; biofoundry; cloud lab; reproducibility; synthetic biology.